ZFIN ID: ZDB-GENE-040912-132
Gene Name: fatty acid binding protein 4a
Gene Symbol: fabp4a    Nomenclature History

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Previous Names: fabp11, fabp11a, fabp4 (1), zgc:103587

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have lipid binding activity. Involved in eye development. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease. Is expressed in several structures, including cardiovascular system; immature eye; muscle; nervous system; and pleuroperitoneal region. Orthologous to several human genes including FABP4 (fatty acid binding protein 4) and FABP5 (fatty acid binding protein 5).
Genome Resources: Alliance (1),  Gene:447944 (1),  Ensembl(GRCz11):ENSDARG00000017299 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-fabp4a
2
CRISPR2-fabp4a
2
MO1-fabp4a N/A 1
MO2-fabp4a N/A 2
DISEASE ASSOCIATED WITH fabp4a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH fabp4a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process eye development (more)
Cellular Component cellular_component (more)
Molecular Function lipid binding (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000463 Cytosolic fatty-acid binding
Domain IPR000566 Lipocalin/cytosolic fatty-acid binding domain
Family IPR031259 Intracellular lipid binding protein
Homologous_superfamily IPR012674 Calycin
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA fabp11a-201 (1)    Ensembl 674
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM fabp4a No data available
MARKER RELATIONSHIPS
fabp4a Contained in: [BAC] DKEY-241P5 (1) (order this)
[Fosmid] CH1073-423L13 (1)
fabp4a Encodes: [cDNA] MGC:103587 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001004682 (1) 687 nt
Genomic GenBank:CT027607 (1) 155409 nt
Select Tool
Polypeptide UniProtKB:Q66I80 (1) 134 aa
Sequence Information (all 11)
ORTHOLOGY for fabp4a ( Chr: 19 )
CITATIONS (59)