ZFIN ID: ZDB-GENE-040912-122
Gene Name: high mobility group box 2b
Gene Symbol: hmgb2b    Nomenclature History

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Previous Names: hmgb2, hmgb2l, im:6909096, wu:fa20b02, zgc:101854

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have DNA binding activity, bending and transcription factor binding activity. Predicted to be involved in several processes, including chromatin remodeling; positive regulation of innate immune response; and positive regulation of transcription by RNA polymerase II. Predicted to localize to cytoplasm and nuclear chromatin. Is expressed in several structures, including axis; gut; neuromast; ovary; and pectoral fin bud. Orthologous to human HMGB2 (high mobility group box 2).
Genome Resources: Alliance (1),  Gene:447936 (1),  Ensembl(GRCz11):ENSDARG00000053990 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6909096]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-hmgb2b N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hmgb2b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH hmgb2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process chromatin remodeling (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hmgb2b No data available
MARKER RELATIONSHIPS
hmgb2b Contained in: [BAC] DKEY-184C2 (1) (order this)
hmgb2b Encodes: [EST] fa20b02, IMAGE:6909096 (1)
[cDNA] MGC:101854 (1), MGC:173789 (1), MGC:192325 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001004674 (1) 911 nt
Genomic GenBank:BX511057 25902 nt
Select Tool
Polypeptide UniProtKB:A7YYD4 (1) 214 aa
Sequence Information (all 20)
ORTHOLOGY for hmgb2b ( Chr: 23 )
CITATIONS (26)