Gene

aldh3a2b

ID
ZDB-GENE-040912-103
Name
aldehyde dehydrogenase 3 family, member A2b
Symbol
aldh3a2b Nomenclature History
Previous Names
  • zgc:103715 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in cellular aldehyde metabolic process. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in intestinal bulb; liver; and notochord. Human ortholog(s) of this gene implicated in Sjogren-Larsson syndrome and arteriosclerosis. Orthologous to human ALDH3A1 (aldehyde dehydrogenase 3 family member A1) and ALDH3A2 (aldehyde dehydrogenase 3 family member A2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aldh3a2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Sjogren-Larsson syndrome Alliance Sjogren-Larsson syndrome 270200
Associated With aldh3a2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR016160 Aldehyde dehydrogenase, cysteine active site
Conserved_site IPR029510 Aldehyde dehydrogenase, glutamic acid active site
Domain IPR015590 Aldehyde dehydrogenase domain
Family IPR012394 Aldehyde dehydrogenase NAD(P)-dependent
Homologous_superfamily IPR016161 Aldehyde/histidinol dehydrogenase
Homologous_superfamily IPR016162 Aldehyde dehydrogenase, N-terminal
Homologous_superfamily IPR016163 Aldehyde dehydrogenase, C-terminal
Domain Details Per Protein
Protein Length Aldehyde dehydrogenase, C-terminal Aldehyde dehydrogenase, cysteine active site Aldehyde dehydrogenase domain Aldehyde dehydrogenase, glutamic acid active site Aldehyde dehydrogenase NAD(P)-dependent Aldehyde dehydrogenase, N-terminal Aldehyde/histidinol dehydrogenase
UniProtKB:E9QH31 490
UniProtKB:Q66I60 169
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations