Gene
wdr18
- ID
- ZDB-GENE-040905-4
- Name
- WD repeat domain 18
- Symbol
- wdr18 Nomenclature History
- Previous Names
-
- wu:fa16f06
- wu:fb79d07
- zgc:92370
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Involved in Kupffer's vesicle development and determination of left/right symmetry. Predicted to localize to Rix1 complex and nuclear pre-replicative complex. Is expressed in Kupffer's vesicle; forerunner cell group; liver; and pancreas. Orthologous to human WDR18 (WD repeat domain 18).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92370 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Gao et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR026987 | WD repeat-containing protein 18, C-terminal domain |
| Family | IPR045227 | WD repeat-containing protein WDR18/Ipi3/RID3 |
| Homologous_superfamily | IPR011047 | Quinoprotein alcohol dehydrogenase-like superfamily |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | G-protein beta WD-40 repeat | Quinoprotein alcohol dehydrogenase-like superfamily | WD40 repeat | WD40 repeat, conserved site | WD40/YVTN repeat-like-containing domain superfamily | WD repeat-containing protein 18, C-terminal domain | WD repeat-containing protein WDR18/Ipi3/RID3 |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:B2GT94
|
431 | |||||||
|
UniProtKB:Q68EI0
|
431 |
Interactions and Pathways
No data available
Plasmids
No data available