Gene

hsd17b1

ID
ZDB-GENE-040901-5
Name
hydroxysteroid (17-beta) dehydrogenase 1
Symbol
hsd17b1 Nomenclature History
Previous Names
  • zfHSD17B1 (1)
  • zf 1.2 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Enables estradiol 17-beta-dehydrogenase activity. Acts upstream of or within androgen metabolic process and estrogen biosynthetic process. Predicted to be located in cytoplasm. Is expressed in brain and gonad. Orthologous to human HSD17B1 (hydroxysteroid 17-beta dehydrogenase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hsd17b1 Human Ortholog
No data available
Associated With hsd17b1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002347 Short-chain dehydrogenase/reductase SDR
Family IPR011348 17beta-dehydrogenase
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length 17beta-dehydrogenase NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase SDR
UniProtKB:F1QUP2 293
UniProtKB:B3DK36 293
UniProtKB:Q7T2J0 295
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations