ZFIN ID: ZDB-GENE-040831-2
Gene Name: epithelial cell transforming 2
Gene Symbol: ect2    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have Rac guanyl-nucleotide exchange factor activity. Involved in cytokinetic process. Predicted to localize to cell cortex and nucleus. Is expressed in midbrain. Orthologous to human ECT2 (epithelial cell transforming 2).
Genome Resources: Alliance (1),  Gene:445406 (1),  Ensembl(GRCz11):ENSDARG00000007278 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi3820aTg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35030 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41785 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • DISEASE ASSOCIATED WITH ect2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ect2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cytokinetic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ect2-201 (1)    Ensembl 3054
    ect2-202 (1)    Ensembl 4186
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ect2
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(hsp70l:FRT-NLS-PhiYFP-FRT-NLS-Cre-2A-dnect2,cryaa:ZsYellow) cryaahsp70l 2ACreect2FRTNLSPhiYFPZsYellow Danio rerio 1 1
    Tg(myl7:EGFP-2A-dnect2) myl7 2Aect2EGFP Danio rerio 1 1
    MARKER RELATIONSHIPS
    ect2 Contained in: [BAC] CH211-153M1 (1)
    ect2 Encodes: [cDNA] MGC:111792 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003883 (1) 3054 nt
    Genomic GenBank:CR759789 (1) 165831 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IKD5 (1) 1012 aa
    Sequence Information (all 31)
    ORTHOLOGY for ect2 ( Chr: 11 )
    CITATIONS (28)