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General Information
ZIRC
ZFIN ID: ZDB-GENE-040827-3
Gene Name: splicing factor 3b, subunit 1
Gene Symbol: sf3b1
Sequence Ontology ID : SO:0000704

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Previous Names: tst, wu:fb99f09

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have mRNA binding activity. Involved in several processes, including hemopoiesis; melanocyte differentiation; and neural crest cell development. Predicted to localize to the nucleus.  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7145777]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b460 Point Mutation Unknown Unknown
hi3394aTg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la010260Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la016554Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa5549 Point Mutation Unknown Splice Site ENU
    sa21516 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27426 Point Mutation Unknown Premature Stop ENU
    sa31725 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44706 Point Mutation Unknown Unknown ENU
    Targeting reagents:
    DISEASE ASSOCIATED WITH sf3b1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    myelodysplastic syndrome Myelodysplastic syndrome, somatic 614286
    DISEASE ASSOCIATED WITH sf3b1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process melanocyte differentiation (more)
    Cellular Component catalytic step 2 spliceosome (more)
    Molecular Function mRNA binding (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA sf3b1-002 (1) 649
    mRNA sf3b1-201 (1) 4644
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM sf3b1 No data available
    MARKER RELATIONSHIPS
    sf3b1Contained in: [BAC] DKEY-83M22 (1) (order this)
    sf3b1Encodes: [EST] fb99f09 (1), IMAGE:7145777 (1) (order this), wz10640 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005167788 (1) 5525bp
    Genomic GenBank:BX530407 (1) 292409bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QQZ1 (1) 1315aa
    Sequence Clusters UniGene:32149 (1)
    Sequence Information (all 32)
    ORTHOLOGY for sf3b1 (Chr: 9)
    CITATIONS (34)