Gene

ift172

ID
ZDB-GENE-040827-1
Name
intraflagellar transport 172
Symbol
ift172 Nomenclature History
Previous Names
  • moe (1)
  • LIM-interacting protein (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Involved in several processes, including animal organ development; photoreceptor cell maintenance; and regulation of TOR signaling. Predicted to localize to axoneme; ciliary basal body; and intraciliary transport particle B. Used to study cystic kidney disease. Human ortholog(s) of this gene implicated in retinitis pigmentosa 71 and short-rib thoracic dysplasia 10 with or without polydactyly. Orthologous to human IFT172 (intraflagellar transport 172).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
23 figures from 15 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ift172 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 71 Alliance Retinitis pigmentosa 71 616394
short-rib thoracic dysplasia 10 with or without polydactyly Alliance Short-rib thoracic dysplasia 10 with or without polydactyly 615630
Associated With ift172 Via Experimental Models
Human Disease Fish Conditions Citations
cystic kidney disease li1Tg + MO3-ift172 control Pandey et al., 2019
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Tetratricopeptide-like helical domain superfamily WD40 repeat WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q5RHH4 1745
UniProtKB:B3DK94 1745
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations