Gene

snrnp70

ID
ZDB-GENE-040825-2
Name
small nuclear ribonucleoprotein 70 (U1)
Symbol
snrnp70 Nomenclature History
Previous Names
  • snrp70
  • U1 small ribonucleoprotein 70kd (1)
  • wu:fc20b04
  • zgc:136450
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have U1 snRNA binding activity and mRNA binding activity. Involved in hematopoietic stem cell differentiation. Predicted to localize to U1 snRNP and U2-type prespliceosome. Is expressed in central nervous system; hematopoietic stem cell; and motor neurons. Human ortholog(s) of this gene implicated in disease of mental health and systemic lupus erythematosus. Orthologous to human SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With snrnp70 Human Ortholog
No data available
Associated With snrnp70 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR022023 U1 small nuclear ribonucleoprotein of 70kDa N-terminal
Domain IPR034143 snRNP70, RNA recognition motif
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain snRNP70, RNA recognition motif U1 small nuclear ribonucleoprotein of 70kDa N-terminal
UniProtKB:Q1ED03 339
UniProtKB:Q503W8 141
UniProtKB:Q6DRE8 495
UniProtKB:Q6DEM1 306
UniProtKB:E7EY23 162
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations