Gene

ak1

ID
ZDB-GENE-040822-37
Name
adenylate kinase 1
Symbol
ak1 Nomenclature History
Previous Names
  • zgc:91930 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have adenylate kinase activity. Predicted to be involved in nucleoside diphosphate phosphorylation and nucleoside triphosphate biosynthetic process. Predicted to localize to cytosol. Is expressed in cephalic musculature; hypaxial myotome region; myotome; pectoral fin musculature; and somite. Human ortholog(s) of this gene implicated in congenital nonspherocytic hemolytic anemia and hemolytic anemia. Orthologous to human AK1 (adenylate kinase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ak1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hemolytic anemia Alliance Hemolytic anemia due to adenylate kinase deficiency 612631
Associated With ak1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR033690 Adenylate kinase, conserved site
Family IPR000850 Adenylate kinase/UMP-CMP kinase
Family IPR006267 Adenylate kinase, isozyme 1/5
Family IPR028582 Adenylate kinase isoenzyme 1
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Adenylate kinase, conserved site Adenylate kinase isoenzyme 1 Adenylate kinase, isozyme 1/5 Adenylate kinase/UMP-CMP kinase P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q68EH2 194
UniProtKB:A0A2R8RXT8 194
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations