ZFIN ID: ZDB-GENE-040822-36
Gene Name: G1 to S phase transition 1
Gene Symbol: gspt1    Nomenclature History

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Previous Name: zgc:91975 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have GTPase activity and translation release factor activity. Predicted to be involved in cytoplasmic translational termination. Predicted to localize to translation release factor complex. Is expressed in axial mesoderm; immature eye; myotome; optic primordium; and retina. Orthologous to several human genes including GSPT1 (G1 to S phase transition 1).
Genome Resources: Alliance (1),  Gene:445485 (1),  Ensembl(GRCz11):ENSDARG00000031048 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2004 [MGC:91975]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010944Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44759 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gspt1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gspt1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cytoplasmic translational termination (more)
    Cellular Component cytosol (more)
    Molecular Function GTPase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gspt1-201 (1)    Ensembl 2723
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gspt1 No data available
    MARKER RELATIONSHIPS
    gspt1 Contained in: [BAC] DKEY-16I5 (1) (order this)
    gspt1 Encodes: [cDNA] MGC:91975 (1), MGC:191762 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003992 (1) 2705 nt
    Genomic GenBank:BX649366 (1) 222310 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8RZF5 (1) 571 aa
    Sequence Information (all 13)
    ORTHOLOGY for gspt1 ( Chr: 12 )
    CITATIONS (22)