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ZIRC
ZFIN ID: ZDB-GENE-040822-32
Gene Name: growth factor receptor-bound protein 10a
Gene Symbol: grb10a
Sequence Ontology ID : SO:0001217

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Previous Names: grb10, zgc:91987

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have SH3/SH2 adaptor activity and insulin receptor binding activity. Predicted to be involved in insulin receptor signaling pathway; negative regulation of Wnt signaling pathway; and  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7142951]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la020680Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa63 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36837 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36838 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH grb10a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH grb10a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of insulin receptor signaling pathway (more)
    Cellular Component cellular_component (more)
    Molecular Function insulin receptor binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA grb10a-202 (1) 2792
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM grb10a No data available
    MARKER RELATIONSHIPS
    grb10a Contained in: [BAC] CH211-243P18 (1) (order this), DKEY-158E13 (1) (order this)
    grb10a Encodes: [EST] IMAGE:7142951 (1) (order this)
    [cDNA] MGC:91987 (1) (order this), MGC:192942 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001004287 (1) 5569 bp
    Genomic GenBank:BX571825 (1) 200814 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q68EG5 (1) 602 aa
    Sequence Clusters UniGene:105808 (1)
    Sequence Information (all 22)
    ORTHOLOGY for grb10a ( Chr: 19 )
    CITATIONS (30)