Gene

grb10a

ID
ZDB-GENE-040822-32
Name
growth factor receptor-bound protein 10a
Symbol
grb10a Nomenclature History
Previous Names
  • grb10
  • zgc:91987
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have insulin receptor binding activity. Predicted to be involved in insulin receptor signaling pathway; negative regulation of Wnt signaling pathway; and negative regulation of insulin receptor signaling pathway. Orthologous to human GRB10 (growth factor receptor bound protein 10).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With grb10a Human Ortholog
No data available
Associated With grb10a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000159 Ras-associating (RA) domain
Domain IPR000980 SH2 domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR015042 BPS (Between PH and SH2) domain
Domain IPR035037 Grb10, SH2
Domain IPR039665 APBB1IP, PH domain
Family IPR035036 Growth factor receptor-bound protein 10
Family IPR039664 GRB/APBB1IP
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length APBB1IP, PH domain BPS (Between PH and SH2) domain Grb10, SH2 GRB/APBB1IP Growth factor receptor-bound protein 10 PH-like domain superfamily Pleckstrin homology domain Ras-associating (RA) domain SH2 domain SH2 domain superfamily Ubiquitin-like domain superfamily
UniProtKB:Q68EG5 602
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations