ZFIN ID: ZDB-GENE-040822-29
Gene Name: ATP/GTP binding protein-like 5
Gene Symbol: agbl5    Nomenclature History

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Previous Names: CCP5 (1), zgc:91997 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have metallocarboxypeptidase activity and tubulin binding activity. Involved in chordate embryonic development and cilium assembly. Predicted to localize to several cellular components, including cytosol; midbody; and mitotic spindle. Is expressed in several structures, including Kupffer's vesicle; axis; forerunner cell group; nervous system; and pronephros. Human ortholog(s) of this gene implicated in retinitis pigmentosa 75. Orthologous to human AGBL5 (ATP/GTP binding protein like 5).
Genome Resources: Alliance (1),  Gene:445479 (1),  Ensembl(GRCz11):ENSDARG00000045900 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12210 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-agbl5 N/A 1
    MO2-agbl5 N/A 2
    MO3-agbl5 N/A 1
    DISEASE ASSOCIATED WITH agbl5 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    retinitis pigmentosa 75 Alliance Retinitis pigmentosa 75 617023
    DISEASE ASSOCIATED WITH agbl5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chordate embryonic development (more)
    Cellular Component cytosol (more)
    Molecular Function metallocarboxypeptidase activity (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA agbl5-201 (1)    Ensembl 3105
    ncRNA agbl5-002 (1)    Ensembl 641
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM agbl5 No data available
    MARKER RELATIONSHIPS
    agbl5 Contained in: [BAC] CH73-39J20 (1)
    agbl5 Encodes: [cDNA] MGC:91997 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001004113 (1) 3125 nt
    Genomic GenBank:CU694451 (1) 111478 nt
    Select Tool
    Polypeptide UniProtKB:F1QNG5 (1) 885 aa
    Sequence Information (all 13)
    ORTHOLOGY for agbl5 ( Chr: 4 )
    CITATIONS (25)