Community Action Needed: Please respond to the NIH RFI
Gene

agbl5

ID
ZDB-GENE-040822-29
Name
AGBL carboxypeptidase 5
Symbol
agbl5 Nomenclature History
Previous Names
  • CCP5 (1)
  • zgc:91997 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable metallocarboxypeptidase activity and tubulin binding activity. Acts upstream of or within chordate embryonic development and cilium assembly. Predicted to be located in several cellular components, including cytosol; midbody; and mitotic spindle. Is expressed in several structures, including Kupffer's vesicle; axis; forerunner cell group; nervous system; and pronephros. Human ortholog(s) of this gene implicated in retinitis pigmentosa 75. Orthologous to human AGBL5 (AGBL carboxypeptidase 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With agbl5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 75 Alliance Retinitis pigmentosa 75 617023
Associated With agbl5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000834 Peptidase M14, carboxypeptidase A
Domain IPR040626 Cytosolic carboxypeptidase, N-terminal
Domain Details Per Protein
Protein Length Cytosolic carboxypeptidase, N-terminal Peptidase M14, carboxypeptidase A
UniProtKB:F1QNG5 885
UniProtKB:Q68EI3 885
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations