Gene

calcrla

ID
ZDB-GENE-040822-26
Name
calcitonin receptor-like a
Symbol
calcrla Nomenclature History
Previous Names
  • CALCRL1 (1)
  • calcrl (1)
  • CLR1 (1)
  • crlr-1 (1)
  • CRLR1 (1)
  • crlr (1)
  • im:7141310
  • zgc:100872 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have calcitonin receptor activity. Involved in blood vessel morphogenesis; chloride ion homeostasis; and somitogenesis. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in hereditary lymphedema. Is expressed in several structures, including cardiovascular system; neural tube; pleuroperitoneal region; trunk; and ventral mesoderm. Orthologous to human CALCRL (calcitonin receptor like receptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With calcrla Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Lymphatic malformation 8 618773
Associated With calcrla Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017983 GPCR, family 2, secretin-like, conserved site
Domain IPR001879 GPCR, family 2, extracellular hormone receptor domain
Domain IPR017981 GPCR, family 2-like
Family IPR000832 GPCR, family 2, secretin-like
Family IPR003287 GPCR, family 2, calcitonin receptor family
Family IPR003289 GPCR, family 2, calcitonin gene-related peptide, type 1 receptor
Homologous_superfamily IPR036445 GPCR family 2, extracellular hormone receptor domain superfamily
Domain Details Per Protein
Protein Length GPCR, family 2, calcitonin gene-related peptide, type 1 receptor GPCR, family 2, calcitonin receptor family GPCR, family 2, extracellular hormone receptor domain GPCR family 2, extracellular hormone receptor domain superfamily GPCR, family 2-like GPCR, family 2, secretin-like GPCR, family 2, secretin-like, conserved site
UniProtKB:Q68EK2 470
UniProtKB:Z4YI91 474
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations