ZFIN ID: ZDB-GENE-040813-1
Gene Name: ring finger protein 114
Gene Symbol: rnf114    Nomenclature History

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Previous Names: znf313, zgc:101076 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity. Human ortholog(s) of this gene implicated in psoriasis 12. Is expressed in olfactory placode; peripheral olfactory organ; and pronephric duct. Orthologous to human RNF114 (ring finger protein 114).
Genome Resources: Alliance (1),  Gene:414843 (1),  Ensembl(GRCz11):ENSDARG00000009886 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [IMAGE:7165258]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37598 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rnf114 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rnf114 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein polyubiquitination (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001841 Zinc finger, RING-type
    Domain IPR008598 Drought induced 19 protein type, zinc-binding domain
    Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
    Conserved_site IPR017907 Zinc finger, RING-type, conserved site
    Domain IPR027370 RING-type zinc-finger, LisH dimerisation motif
    Domain IPR034734 Zinc finger C2HC RNF-type
    Domain IPR042716 E3 ubiquitin-protein ligase RNF114, RING finger, HC subclass
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rnf114-201 (1)    Ensembl 1262
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rnf114 No data available
    MARKER RELATIONSHIPS
    rnf114 Contained in: [BAC] DKEY-9L20 (1) (order this)
    rnf114 Encodes: [EST] IMAGE:7165258 (1)
    [cDNA] MGC:101076
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001828 (1) 1241 bp
    Genomic GenBank:CR759920 (1) 142258 bp
    Select Tool
    Polypeptide UniProtKB:Q6J0N1 (1) 221 aa
    Sequence Information (all 11)
    ORTHOLOGY for rnf114 ( Chr: 23 )
    CITATIONS (21)