Gene
cdkn1ba
- ID
- ZDB-GENE-040812-3
- Name
- cyclin dependent kinase inhibitor 1Ba
- Symbol
- cdkn1ba Nomenclature History
- Previous Names
-
- cdkn1bl (1)
- kip1
- p27
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have chaperone binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Predicted to be involved in G1/S transition of mitotic cell cycle; negative regulation of cell cycle; and negative regulation of cell population proliferation. Predicted to localize to cytoplasm and nucleus. Is expressed in otic vesicle. Human ortholog(s) of this gene implicated in acute myeloid leukemia; breast cancer; multiple endocrine neoplasia type 4; and myelodysplastic syndrome. Orthologous to human CDKN1B (cyclin dependent kinase inhibitor 1B).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
multiple endocrine neoplasia type 4 | Alliance | Multiple endocrine neoplasia, type IV | 610755 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Cyclin-dependent kinase inhibitor domain | Cyclin-dependent kinase inhibitor domain superfamily |
---|---|---|---|
UniProtKB:Q5RGY9
|
187 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
cdkn1ba-201
(1)
|
Ensembl | 2,280 nt | ||
ncRNA |
cdkn1ba-002
(1)
|
Ensembl | 885 nt |
Interactions and Pathways
No data available
Plasmids
No data available