ZFIN ID: ZDB-GENE-040808-68
Gene Name: acetyl-CoA acetyltransferase 1
Gene Symbol: acat1    Nomenclature History

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Previous Names: fd16h07, fd20g06, wu:fd16h07, wu:fd20g06, zgc:86832

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have acetyl-CoA C-acetyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to localize to mitochondrion. Is expressed in liver. Human ortholog(s) of this gene implicated in beta-ketothiolase deficiency and carbohydrate metabolic disorder. Orthologous to human ACAT1 (acetyl-CoA acetyltransferase 1).
Genome Resources: Alliance (1),  Gene:445290 (1),  Ensembl(GRCz11):ENSDARG00000045888 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 7 figures (4 images) from Thisse et al., 2004 [IMAGE:7157078]
Wild-type Stages, Structures: Pharyngula:High-pec (42.0h-48.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH acat1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
beta-ketothiolase deficiency Alliance Alpha-methylacetoacetic aciduria 203750
DISEASE ASSOCIATED WITH acat1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process fatty acid beta-oxidation (more)
Cellular Component mitochondrion (more)
Molecular Function acetyl-CoA C-acetyltransferase activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM acat1 No data available
MARKER RELATIONSHIPS
acat1 Encodes: [EST] fd16h07, fd20g06, IMAGE:7157078 (1)
[cDNA] MGC:86832 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001003746 (1)
Polypeptide UniProtKB:Q6AZA0 (1) 420 aa
Sequence Information (all 14)
ORTHOLOGY for acat1 ( Chr: 10 )
CITATIONS (26)