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General Information
ZIRC
ZFIN ID: ZDB-GENE-040808-67
Gene Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Gene Symbol: kras
Sequence Ontology ID : SO:0000704

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Previous Names: fa04e08, fc14b12, fc23g10, fj89d12, wu:fa04e08, wu:fc14b12, wu:fc23g10, wu:fj89d12, xRAS2 (1), zgc:85725

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(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have GDP binding activity; GTP binding activity; and GTPase activity. Involved in embryonic cranial skeleton morphogenesis; heart development; and hemopoiesis. Predicted to localize to  ...
GENE EXPRESSION
All Expression Data: 2 figures from Liu et al., 2008
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
DISEASE ASSOCIATED WITH kras HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
acute myeloid leukemia Leukemia, acute myeloid 601626
arteriovenous malformations of the brain Arteriovenous malformation of the brain, somatic 108010
autoimmune lymphoproliferative syndrome type 4 RAS-associated autoimmune leukoproliferative disorder 614470
breast cancer Breast cancer, somatic 114480
cardiofaciocutaneous syndrome Cardiofaciocutaneous syndrome 2 615278
lung cancer Lung cancer, somatic 211980
Noonan syndrome 3 Noonan syndrome 3 609942
pancreatic carcinoma Pancreatic carcinoma, somatic 260350
stomach cancer Gastric cancer, somatic 137215
urinary bladder cancer Bladder cancer, somatic 109800
Schimmelpenning-Feuerstein-Mims syndrome, somatic mosaic 163200
DISEASE ASSOCIATED WITH kras VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic cranial skeleton morphogenesis (more)
Cellular Component membrane (more)
Molecular Function GTPase activity (more)
GO Terms (all 11)
TRANSCRIPTS No data available
GENE PRODUCT DESCRIPTION No description available
INTERACTIONS AND PATHWAYS
SignaFish
ANTIBODIESNo data available
PLASMIDSNo data available
MARKER RELATIONSHIPS
krasEncodes: [EST] fa04e08, fc14b12, fc23g10, fj89d12
[cDNA] MGC:85725 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001003744 (1) 6959bp
Genomic GenBank:FO904995 (1) 32594bp
Select Tool
Polypeptide UniProtKB:A0A2R8Q8S1 (1) 189aa
Sequence Clusters UniGene:20193 (1)
Sequence Information (all 26)
OTHER kras GENE PAGES
  • Alliance (1)
  • Gene:445289 (1)
  • Ensembl(GRCz11):ENSDARG00000010844 (2)
  • ORTHOLOGY for kras (Chr: 25)
    CITATIONS (62)