ZFIN ID: ZDB-GENE-040808-52
Gene Name: CD81 molecule b
Gene Symbol: cd81b    Nomenclature History

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Previous Name: zgc:92411

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to localize to integral component of plasma membrane. Is expressed in cerebellum; cleithrum; floor plate; and hindbrain. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human CD81 (CD81 molecule).
Genome Resources: Alliance (1),  Gene:445280 (1),  Ensembl(GRCz11):ENSDARG00000022437 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [MGC:92411]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32210 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43122 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cd81b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    common variable immunodeficiency Alliance Immunodeficiency, common variable, 6 613496
    DISEASE ASSOCIATED WITH cd81b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component integral component of membrane (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cd81b-201 (1)    Ensembl 1365
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cd81b No data available
    MARKER RELATIONSHIPS
    cd81b Contained in: [BAC] DKEY-29P10 (1) (order this)
    cd81b Encodes: [cDNA] MGC:92411 (1), MGC:192256 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003735 (1) 1330 nt
    Genomic GenBank:BX640463 (1) 233058 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q6AZB9 (1) 238 aa
    Sequence Information (all 14)
    ORTHOLOGY for cd81b ( Chr: 18 )
    CITATIONS (19)