ZFIN ID: ZDB-GENE-040801-63
Gene Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Gene Symbol: lamtor2    Nomenclature History

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Previous Name: zgc:100811 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in several processes, including cellular response to amino acid stimulus; positive regulation of TOR signaling; and regulation of cell growth. Predicted to localize to Ragulator complex. Orthologous to human LAMTOR2 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 2).
Genome Resources: Alliance (1),  Gene:445155 (1),  Ensembl(GRCz11):ENSDARG00000039872 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa39128 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lamtor2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Immunodeficiency due to defect in MAPBP-interacting protein 610798
    DISEASE ASSOCIATED WITH lamtor2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular protein localization (more)
    Cellular Component late endosome (more)
    Molecular Function CONTRIBUTES_TO   guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lamtor2-201 (1)    Ensembl 785
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lamtor2 No data available
    MARKER RELATIONSHIPS
    lamtor2 Contained in: [BAC] DKEY-185P18 (1) (order this)
    lamtor2 Encodes: [cDNA] MGC:100811 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003549 (1) 800 nt
    Genomic GenBank:BX323793 (1) 170199 nt
    Select Tool
    Polypeptide UniProtKB:F1R3H0 (1) 125 aa
    Sequence Information (all 12)
    ORTHOLOGY for lamtor2 ( Chr: 16 )
    CITATIONS (23)