ZFIN ID: ZDB-GENE-040801-58
Gene Name: ectonucleoside triphosphate diphosphohydrolase 1
Gene Symbol: entpd1    Nomenclature History

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Previous Names: NTPDase1 (1), zgc:100819

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and hydrolase activity. Involved in cellular response to methanol; response to copper ion; and response to ethanol. Predicted to localize to integral component of membrane. Is expressed in several structures, including cardiovascular system; digestive system; hindbrain neural plate; nervous system; and periderm. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 64. Orthologous to human ENTPD1 (ectonucleoside triphosphate diphosphohydrolase 1).
Genome Resources: Alliance (1),  Gene:445151 (1),  Ensembl(GRCz11):ENSDARG00000045066 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16712 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17164 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22131 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-entpd1 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH entpd1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    hereditary spastic paraplegia 64 Alliance Spastic paraplegia 64, autosomal recessive 615683
    DISEASE ASSOCIATED WITH entpd1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to methanol (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA entpd1-201 (1)    Ensembl 2420
    entpd1-203 (1)    Ensembl 796
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM entpd1 No data available
    MARKER RELATIONSHIPS
    entpd1 Contained in: [BAC] CH211-140C18 (1)
    entpd1 Encodes: [EST] IMAGE:7151329 (1)
    [cDNA] MGC:100819 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003545 (1) 2450 nt
    Genomic GenBank:CR354534 (1) 189794 nt
    Select Tool
    Polypeptide UniProtKB:E7FG27 (1) 496 aa
    Sequence Information (all 14)
    ORTHOLOGY for entpd1 ( Chr: 12 )
    CITATIONS (41)