Community Action Needed: Please respond to the NIH RFI
Gene

brf2

ID
ZDB-GENE-040801-43
Name
BRF2 RNA polymerase III transcription initiation factor subunit
Symbol
brf2 Nomenclature History
Previous Names
  • si:ch211-271b8.2
  • wu:fj22c04
  • zgc:100856
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable RNA polymerase III type 3 promoter sequence-specific DNA binding activity and TBP-class protein binding activity. Predicted to be involved in DNA-templated transcription, initiation; cellular response to oxidative stress; and regulation of transcription by RNA polymerase III. Predicted to act upstream of or within transcription preinitiation complex assembly. Predicted to be part of transcription factor TFIIIB complex and transcription preinitiation complex. Predicted to be active in nucleus. Orthologous to human BRF2 (BRF2 RNA polymerase III transcription initiation factor subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With brf2 Human Ortholog
No data available
Associated With brf2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013137 Zinc finger, TFIIB-type
Family IPR000812 Transcription factor TFIIB
Homologous_superfamily IPR036915 Cyclin-like superfamily
Domain Details Per Protein
Protein Length Cyclin-like superfamily Transcription factor TFIIB Zinc finger, TFIIB-type
UniProtKB:A8KBY2 423
UniProtKB:F1QD13 354
UniProtKB:F1QIW1 423
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations