Gene

bag3

ID
ZDB-GENE-040801-40
Name
BCL2 associated athanogene 3
Symbol
bag3 Nomenclature History
Previous Names
  • zgc:100859
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have adenyl-nucleotide exchange factor activity; chaperone binding activity; and heat shock protein binding activity. Involved in heart contraction; locomotory behavior; and skeletal muscle tissue development. Localizes to Z disc. Is expressed in fast muscle cell; heart; muscle; and slow muscle cell. Used to study muscular dystrophy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1HH and myofibrillar myopathy 6. Orthologous to human BAG3 (BAG cochaperone 3).
Genome Resources
Note
None
Expression
All Expression Data
5 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bag3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
dilated cardiomyopathy 1HH Alliance Cardiomyopathy, dilated, 1HH 613881
myofibrillar myopathy 6 Alliance Myopathy, myofibrillar, 6 612954
Associated With bag3 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001202 WW domain
Domain IPR003103 BAG domain
Family IPR039773 Molecular chaperone regulator BAG
Homologous_superfamily IPR036020 WW domain superfamily
Homologous_superfamily IPR036533 BAG domain superfamily
Domain Details Per Protein
Protein Length BAG domain BAG domain superfamily Molecular chaperone regulator BAG WW domain WW domain superfamily
UniProtKB:F1Q9J0 480
UniProtKB:Q6DC38 459
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations