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ZIRC
ZFIN ID: ZDB-GENE-040801-40
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Gene Name: BCL2 associated athanogene 3
Gene Symbol: bag3
Sequence Ontology ID : SO:0001217

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Previous Name: zgc:100859

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have chaperone binding activity. Involved in heart contraction; locomotory behavior; and skeletal muscle tissue development. Localizes to the Z disc. Used to study muscular dystrophy.  ...
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Wild-type Stages, Structures: Segmentation:10-13 somites (14.0h-16.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6304 Point Mutation Unknown Premature Stop ENU
sa22301 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa35490 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa38940 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa42208 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 6 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH bag3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    dilated cardiomyopathy 1HH Cardiomyopathy, dilated, 1HH 613881
    myofibrillar myopathy 6 Myopathy, myofibrillar, 6 612954
    DISEASE ASSOCIATED WITH bag3 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    muscular dystrophy WT + MO4-bag3 standard conditions Ruparelia et al., 2014
    WT + MO3-bag3 + MO4-bag3 standard conditions Ruparelia et al., 2014
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heart contraction (more)
    Cellular Component Z disc (more)
    Molecular Function chaperone binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001202 (1)
  • InterPro:IPR003103 (1)
  • InterPro:IPR036020 (1)
  • InterPro:IPR036533 (1)
  • InterPro:IPR039773 (1)
  • PROSITE:PS01159 (1)
  • PROSITE:PS50020 (1)
  • PROSITE:PS51035 (1)
  • Pfam:PF00397 (1)
  • Pfam:PF02179 (1)
    • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA bag3-201 (1) 2239
    Select Tool
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bag3 No data available
    MARKER RELATIONSHIPS
    bag3 Contained in: [BAC] DKEY-51A16 (order this)
    bag3 Encodes: [EST] wz12756
    [cDNA] MGC:100859 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001003533 (1) 2175 bp
    Select Tool
    Genomic GenBank:BX530079 (1) 166397 bp
    Select Tool
    Polypeptide UniProtKB:F1Q9J0 (1) 480 aa
    Select Tool
    Sequence Clusters UniGene:79182 (1)
    Sequence Information (all 12)
    OTHER bag3 GENE PAGES
  • Alliance (1)
  • Gene:445139 (1)
  • VEGA:OTTDARG00000018247 (1)
  • Ensembl(GRCz11):ENSDARG00000039486 (2)
    • ORTHOLOGY for bag3 ( Chr: 13 )
    CITATIONS (24)