Gene

hadh

ID
ZDB-GENE-040801-261
Name
hydroxyacyl-CoA dehydrogenase
Symbol
hadh Nomenclature History
Previous Names
  • hoad (1)
  • hadhsc (1)
  • wu:fb66a11
  • zgc:86777
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have 3-hydroxyacyl-CoA dehydrogenase activity and NAD+ binding activity. Predicted to be involved in fatty acid metabolic process and oxidation-reduction process. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 4. Orthologous to human HADH (hydroxyacyl-CoA dehydrogenase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hadh Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial hyperinsulinemic hypoglycemia 4 Alliance Hyperinsulinemic hypoglycemia, familial, 4 609975
3-hydroxyacyl-CoA dehydrogenase deficiency 231530
Associated With hadh Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site
Domain IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal
Domain IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding
Family IPR022694 3-hydroxyacyl-CoA dehydrogenase
Homologous_superfamily IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
Homologous_superfamily IPR013328 6-phosphogluconate dehydrogenase, domain 2
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length 3-hydroxyacyl-CoA dehydrogenase 3-hydroxyacyl-CoA dehydrogenase, conserved site 3-hydroxyacyl-CoA dehydrogenase, C-terminal 3-hydroxyacyl-CoA dehydrogenase, NAD binding 6-phosphogluconate dehydrogenase, domain 2 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily NAD(P)-binding domain superfamily
UniProtKB:Q6DI22 309
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations