Gene
alkbh3
- ID
- ZDB-GENE-040801-254
- Name
- alkB homolog 3, alpha-ketoglutarate dependent dioxygenase
- Symbol
- alkbh3 Nomenclature History
- Previous Names
-
- im:6900103
- zgc:91935 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have dioxygenase activity. Predicted to be involved in DNA dealkylation involved in DNA repair and oxidative single-stranded DNA demethylation. Predicted to localize to nucleus. Orthologous to human ALKBH3 (alkB homolog 3, alpha-ketoglutaratedependent dioxygenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6900103 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Kuang et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005123 | Oxoglutarate/iron-dependent dioxygenase |
| Domain | IPR027450 | Alpha-ketoglutarate-dependent dioxygenase AlkB-like |
| Family | IPR032854 | Alkylated DNA repair protein alkB homologue 3 |
| Homologous_superfamily | IPR037151 | Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily |
Domain Details Per Protein
| Protein | Length | Alkylated DNA repair protein alkB homologue 3 | Alpha-ketoglutarate-dependent dioxygenase AlkB-like | Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily | Oxoglutarate/iron-dependent dioxygenase |
|---|---|---|---|---|---|
|
UniProtKB:F1QRD8
|
|||||
|
UniProtKB:A0A8M2BAA9
|
236 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
alkbh3-201
(1)
|
Havana | 1475 nt | |
| mRNA |
alkbh3-203
(1)
|
Havana | 778 nt | |
| mRNA |
alkbh3-204
(1)
|
Havana | 541 nt | |
| mRNA |
alkbh3-205
(1)
|
Havana | 423 nt |
Interactions and Pathways
No data available
Plasmids
No data available