Gene

pkmb

ID
ZDB-GENE-040801-230
Name
pyruvate kinase M1/2b
Symbol
pkmb Nomenclature History
Previous Names
  • pkm2b
  • zgc:92037 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have pyruvate kinase activity. Predicted to be involved in cellular response to insulin stimulus and glycolytic process. Predicted to localize to cytoplasm. Is expressed in myotome and pectoral fin musculature. Orthologous to human PKM (pyruvate kinase M1/2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pkmb Human Ortholog
No data available
Associated With pkmb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018209 Pyruvate kinase, active site
Domain IPR015793 Pyruvate kinase, barrel
Domain IPR015795 Pyruvate kinase, C-terminal
Family IPR001697 Pyruvate kinase
Homologous_superfamily IPR011037 Pyruvate kinase-like, insert domain superfamily
Homologous_superfamily IPR015806 Pyruvate kinase, insert domain superfamily
Homologous_superfamily IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily
Homologous_superfamily IPR036918 Pyruvate kinase, C-terminal domain superfamily
Homologous_superfamily IPR040442 Pyruvate kinase-like domain superfamily
Domain Details Per Protein
Protein Length Pyruvate kinase Pyruvate kinase, active site Pyruvate kinase, barrel Pyruvate kinase, C-terminal Pyruvate kinase, C-terminal domain superfamily Pyruvate kinase, insert domain superfamily Pyruvate kinase-like domain superfamily Pyruvate kinase-like, insert domain superfamily Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily
UniProtKB:A0A0R4IHV1 530
UniProtKB:Q6DG54 530
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations