ZFIN ID: ZDB-GENE-040801-220
Gene Name: RasGEF domain family, member 1Bb
Gene Symbol: rasgef1bb    Nomenclature History

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Previous Names: fc34e01, rasgef (1), im:7136415, wu:fc34e01, zgc:91814

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have Ras guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Is expressed in nervous system; notochord; oocyte; pectoral fin; and pharyngeal arch. Orthologous to human RASGEF1B (RasGEF domain family member 1B).
Genome Resources: Alliance (1),  Gene:445085 (1),  Ensembl(GRCz11):ENSDARG00000044251 (1)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 6 figures (18 images) from Thisse et al., 2004 [MGC:91814]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7136415]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH rasgef1bb HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH rasgef1bb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process small GTPase mediated signal transduction (more)
Molecular Function Ras guanyl-nucleotide exchange factor activity (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal
Domain IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
Family IPR008937 Ras-like guanine nucleotide exchange factor
Conserved_site IPR019804 Ras guanine-nucleotide exchange factor, conserved site
Homologous_superfamily IPR023578 Ras guanine nucleotide exchange factor domain superfamily
Homologous_superfamily IPR036964 Ras guanine-nucleotide exchange factor catalytic domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA rasgef1bb-201 (1)    Ensembl 2173
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM rasgef1bb No data available
MARKER RELATIONSHIPS
rasgef1bb Contained in: [BAC] DKEYP-41F9 (1)
rasgef1bb Encodes: [EST] fc34e01, IMAGE:7136415 (1)
[cDNA] MGC:91814 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001003479 (1) 2090 bp
Genomic GenBank:BX323017 (1) 141192 bp
Select Tool
Polypeptide UniProtKB:Q6DBW1 (1) 475 aa
Sequence Information (all 11)
ORTHOLOGY for rasgef1bb ( Chr: 10 )
CITATIONS (22)