ZFIN ID: ZDB-GENE-040801-196
Gene Name: corticotropin releasing hormone binding protein
Gene Symbol: crhbp    Nomenclature History

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Previous Names: CRF-BP (1), zgc:91905 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have corticotropin-releasing hormone binding activity. Predicted to be involved in hormone-mediated signaling pathway; negative regulation of corticotropin secretion; and negative regulation of corticotropin-releasing hormone receptor activity. Predicted to localize to extracellular space. Is expressed in brain; neurons; and retina. Human ortholog(s) of this gene implicated in mental depression. Orthologous to human CRHBP (corticotropin releasing hormone binding protein).
Genome Resources: Alliance (1),  Gene:445065 (1),  Ensembl(GRCz11):ENSDARG00000024831 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32332 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH crhbp HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH crhbp VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hormone-mediated signaling pathway (more)
    Cellular Component extracellular region (more)
    Molecular Function corticotropin-releasing hormone binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM crhbp No data available
    MARKER RELATIONSHIPS
    crhbp Encodes: [EST] IMAGE:6907482 (1)
    [cDNA] MGC:91905 (1), MGC:191297 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003459 (1)
    Genomic GenBank:CABZ01034874 (1) 6438 nt
    Polypeptide UniProtKB:Q6DG79 (1) 321 aa
    Sequence Information (all 17)
    ORTHOLOGY for crhbp ( Chr: 21 )
    CITATIONS (46)