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General Information
ZIRC
ZFIN ID: ZDB-GENE-040801-178
Gene Name: dynein, axonemal, light chain 1
Gene Symbol: dnal1    Nomenclature History

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Previous Names: fc89a04, wu:fc89a04, zgc:92542

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have alpha-tubulin binding activity; dynein heavy chain binding activity; and motor activity. Predicted to be involved in outer dynein arm assembly. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 16. Orthologous to human DNAL1 (dynein axonemal light chain 1).
Genome Resources: Alliance (1),  Gene:445048 (1), 
GENE EXPRESSION
All Expression Data: Fig. 2 from Zhao et al., 2013
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12375 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39169 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dnal1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    primary ciliary dyskinesia 16 Alliance Ciliary dyskinesia, primary, 16 614017
    DISEASE ASSOCIATED WITH dnal1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process outer dynein arm assembly (more)
    Cellular Component cell projection (more)
    Molecular Function motor activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001611 (1)
  • InterPro:IPR032675 (1)
  • PROSITE:PS51450 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dnal1-001 (1) 1615
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dnal1 No data available
    MARKER RELATIONSHIPS
    dnal1 Contained in: [BAC] CH211-237F6 (1) (order this), DKEY-84K17 (1) (order this)
    dnal1 Encodes: [EST] fc89a04
    [cDNA] MGC:92542 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001003442 (1) 1621 bp
    Genomic GenBank:BX957235 (1) 171764 bp
    Select Tool
    Polypeptide UniProtKB:Q6DHB1 (1) 192 aa
    Sequence Clusters UniGene:79591 (1)
    Sequence Information (all 14)
    ORTHOLOGY for dnal1 ( Chr: 17 )
    CITATIONS (15)