Gene

hbba2

ID

ZDB-GENE-040801-164

Name

hemoglobin, beta adult 2

Symbol

hbba2 Nomenclature History

Previous Names

fj42e02
si:ch211-5k11.13
si:xx-by187g17.6
wu:fj42e02
zgc:113872
zgc:92880

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to contribute to haptoglobin binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to localize to haptoglobin-hemoglobin complex and hemoglobin complex. Human ortholog(s) of this gene implicated in acute chest syndrome; hemolytic anemia (multiple); malaria; polycythemia (multiple); and sickle cell anemia. Is expressed in female organism and vasculature. Orthologous to several human genes including HBE1 (hemoglobin subunit epsilon 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UCSC scRNA-seq

Thisse Expression Data

MGC:92880 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hbba2 Human Ortholog

No data available

Associated With hbba2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000971	Globin
Family	IPR002337	Haemoglobin, beta-type
Homologous_superfamily	IPR009050	Globin-like superfamily
Homologous_superfamily	IPR012292	Globin/Protoglobin