Gene

timm8a

ID
ZDB-GENE-040801-158
Name
translocase of inner mitochondrial membrane 8 homolog A (yeast)
Symbol
timm8a Nomenclature History
Previous Names
  • im:6896085
  • zgc:100916
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have metal ion binding activity. Predicted to be involved in chaperone-mediated protein transport. Predicted to localize to mitochondrial inner membrane and mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in deafness-dystonia-optic neuronopathy syndrome and dystonia. Orthologous to human TIMM8A (translocase of inner mitochondrial membrane 8A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With timm8a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
deafness-dystonia-optic neuronopathy syndrome Alliance Mohr-Tranebjaerg syndrome 304700
Associated With timm8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004217 Tim10-like
Family IPR039238 Mitochondrial import inner membrane translocase subunit Tim8/13
Homologous_superfamily IPR035427 Tim10-like domain superfamily
Domain Details Per Protein
Protein Length Mitochondrial import inner membrane translocase subunit Tim8/13 Tim10-like Tim10-like domain superfamily
UniProtKB:A0A2R8QFA6 96
UniProtKB:A0A2R8RNM0 99
UniProtKB:Q6DEM5 90
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations