ZFIN ID: ZDB-GENE-040801-147
Gene Name: malic enzyme 2, NAD(+)-dependent, mitochondrial
Gene Symbol: me2    Nomenclature History

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Previous Name: zgc:100941

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have malate dehydrogenase (decarboxylating) (NADP+) activity. Predicted to be involved in malate metabolic process and pyruvate metabolic process. Predicted to localize to mitochondrion. Is expressed in several structures, including cardiovascular system; hatching gland; musculature system; polster; and visual system. Orthologous to human ME2 (malic enzyme 2).
Genome Resources: Alliance (1),  Gene:445233 (1),  Ensembl(GRCz11):ENSDARG00000100718 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH me2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH me2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component mitochondrion (more)
Molecular Function malate dehydrogenase (decarboxylating) (NAD+) activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA me2-201 (1)    Ensembl 2092
me2-202 (1)    Ensembl 490
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM me2 No data available
MARKER RELATIONSHIPS
me2 Contained in: [BAC] CH73-49H18 (1), DKEYP-87D7 (1)
me2 Encodes: [EST] IMAGE:7146407 (1)
[cDNA] MGC:100941 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001003627 (1) 1915 nt
Genomic GenBank:CT955987 (1) 182912 nt
Select Tool
Polypeptide UniProtKB:A5PN55 (1) 581 aa
Sequence Information (all 13)
ORTHOLOGY for me2 ( Chr: 5 )
CITATIONS (19)