Gene

mastl

ID
ZDB-GENE-040801-128
Name
microtubule associated serine/threonine kinase-like
Symbol
mastl Nomenclature History
Previous Names
  • im:7149025
  • wu:fa02a12
  • zgc:100990
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have protein phosphatase 2A binding activity and protein serine/threonine kinase activity. Involved in thrombocyte differentiation. Predicted to localize to centrosome; cleavage furrow; and nucleus. Human ortholog(s) of this gene implicated in thrombocytopenia. Is expressed in somite. Orthologous to human MASTL (microtubule associated serine/threonine kinase like).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Johnson et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mastl Human Ortholog
No data available
Associated With mastl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR037638 Serine/threonine-protein kinase greatwall, catalytic domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Serine/threonine-protein kinase greatwall, catalytic domain
UniProtKB:Q6DBX4 860
UniProtKB:A3KNA9 738
UniProtKB:F1R778 860
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations