ZFIN ID: ZDB-GENE-040801-128
Gene Name: microtubule associated serine/threonine kinase-like
Gene Symbol: mastl    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: im:7149025, wu:fa02a12, zgc:100990

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have protein phosphatase 2A binding activity and protein serine/threonine kinase activity. Involved in thrombocyte differentiation. Predicted to localize to centrosome; cleavage furrow; and nucleus. Is expressed in somite. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human MASTL (microtubule associated serine/threonine kinase like).
Genome Resources: Alliance (1),  Gene:445215 (1),  Ensembl(GRCz11):ENSDARG00000055566 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7147285]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7149025]
  6 figures (5 images) from Thisse et al., 2004 [IMAGE:7143273]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028662Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-mastl N/A 1
    MO2-mastl N/A 1
    DISEASE ASSOCIATED WITH mastl HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mastl VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process thrombocyte differentiation (more)
    Cellular Component centrosome (more)
    Molecular Function protein phosphatase 2A binding (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mastl-201 (1)    Ensembl 3081
    ncRNA mastl-002 (1)    Ensembl 1010
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mastl No data available
    MARKER RELATIONSHIPS
    mastl Contained in: [BAC] CH211-193E5 (1)
    mastl Encodes: [EST] fa02a12, IMAGE:7143273 (1), IMAGE:7147285 (1), IMAGE:7149025 (1)
    [cDNA] MGC:100990 (1), MGC:158577 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003609 (1) 3080 nt
    Genomic GenBank:CT573382 (1) 56784 nt
    Select Tool
    Polypeptide UniProtKB:F1R778 (1) 860 aa
    Sequence Information (all 22)
    ORTHOLOGY for mastl ( Chr: 24 )
    CITATIONS (26)