Gene

gabrr1

ID

ZDB-GENE-040724-212

Name

gamma-aminobutyric acid type A receptor subunit rho1

Symbol

gabrr1 Nomenclature History

Previous Names

si:dkey-77b17.3

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to contribute to GABA-A receptor activity and chloride channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; chloride transmembrane transport; and regulation of membrane potential. Predicted to localize to several cellular components, including GABA-A receptor complex; integral component of plasma membrane; and neuron projection. Is expressed in diencephalon and eye. Orthologous to human GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1).

Genome Resources

Note

None

Expression

All Expression Data

1 figure from Cocco et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gabrr1 Human Ortholog

No data available

Associated With gabrr1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018000	Neurotransmitter-gated ion-channel, conserved site
Domain	IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
Domain	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain
Family	IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha
Family	IPR006201	Neurotransmitter-gated ion-channel
Homologous_superfamily	IPR036719	Neurotransmitter-gated ion-channel transmembrane domain superfamily
Homologous_superfamily	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily

Domain Details Per Protein

Protein	Length	Gamma-aminobutyric acid A receptor/Glycine receptor alpha	Neurotransmitter-gated ion-channel	Neurotransmitter-gated ion-channel, conserved site	Neurotransmitter-gated ion-channel ligand-binding domain	Neurotransmitter-gated ion-channel ligand-binding domain superfamily	Neurotransmitter-gated ion-channel transmembrane domain	Neurotransmitter-gated ion-channel transmembrane domain superfamily
UniProtKB:R4GE21 InterPro	193
UniProtKB:Q5TZ16 InterPro	466

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	gabrr1-201 (1) Ensembl	1548 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	gabrr1-202 (1) Ensembl	578 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Gene Tree: Ensembl

Citations