Gene

kdm6bb

ID
ZDB-GENE-040724-166
Name
lysine (K)-specific demethylase 6B, b
Symbol
kdm6bb Nomenclature History
Previous Names
  • kdm6b
  • jmjd3
  • jmjd3a (1)
  • si:ch211-237l4.7
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Exhibits H3K27me3 modified histone binding activity and histone demethylase activity (H3-K27 specific). Involved in several processes, including common myeloid progenitor cell proliferation; fin regeneration; and primitive erythrocyte differentiation. Predicted to localize to MLL3/4 complex. Is expressed in brain; caudal hematopoietic tissue; heart; otic vesicle; and spinal cord. Orthologous to human KDM6B (lysine demethylase 6B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kdm6bb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities 618505
Associated With kdm6bb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003347 JmjC domain
Family IPR029518 Lysine-specific demethylase 6B
Domain Details Per Protein
Protein Length JmjC domain Lysine-specific demethylase 6B
UniProtKB:E9QG91 1719
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations