ZFIN is now using GRCz12tu for Genomic Data
Gene
sart3
- ID
- ZDB-GENE-040724-10
- Name
- spliceosome associated factor 3, U4/U6 recycling protein
- Symbol
- sart3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable U6 snRNA binding activity and histone binding activity. Involved in spliceosomal snRNP assembly. Acts upstream of or within several processes, including gland development; hematopoietic stem cell homeostasis; and spliceosomal complex assembly. Predicted to be located in Cajal body and nuclear speck. Predicted to be part of ASAP complex. Predicted to be active in cytoplasm and nucleoplasm. Predicted to colocalize with U4/U6 snRNP and U6atac snRNP. Orthologous to human SART3 (spliceosome associated factor 3, U4/U6 recycling protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151848 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR008847 | Suppressor of forked |
| Domain | IPR034217 | SART3, RNA recognition motif 1 |
| Domain | IPR034218 | SART3, RNA recognition motif 2 |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
| Repeat | IPR003107 | HAT (Half-A-TPR) repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | HAT (Half-A-TPR) repeat | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | SART3, RNA recognition motif 1 | SART3, RNA recognition motif 2 | Suppressor of forked | Tetratricopeptide-like helical domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6ZM52 | InterPro | 951 | ||||||||
| UniProtKB:B3DJT0 | InterPro | 951 | ||||||||
| UniProtKB:A0AB32TR34 | InterPro | 951 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers