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ZIRC
ZFIN ID: ZDB-GENE-040718-96
Gene Name: pyruvate dehydrogenase E1 alpha 1 subunit b
Gene Symbol: pdha1b
Sequence Ontology ID : SO:0000704

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Previous Names: fp73b04, wu:fp73b04, zgc:92705 (1)

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have pyruvate dehydrogenase (acetyl-transferring) activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate and oxidation-reduction process. Predicted to  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92705]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37894 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39453 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pdha1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    pyruvate decarboxylase deficiency Pyruvate dehydrogenase E1-alpha deficiency 312170
    DISEASE ASSOCIATED WITH pdha1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process acetyl-CoA biosynthetic process from pyruvate (more)
    Cellular Component intracellular membrane-bounded organelle (more)
    Molecular Function oxidoreductase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001017 (1)
  • InterPro:IPR017597 (1)
  • InterPro:IPR029061 (1)
  • Pfam:PF00676 (1)
  • EC:1.2.4.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pdha1b-201 (1) 1712
    pdha1b-203 (1) 543
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pdha1b No data available
    MARKER RELATIONSHIPS
    pdha1bContained in: [BAC] DKEY-226L10 (1) (order this)
    pdha1bEncodes: [EST] fp73b04
    [cDNA] MGC:92705 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002399 (1) 1727bp
    Genomic GenBank:BX649452 (1) 192113bp
    Select Tool
    Polypeptide UniProtKB:E7F9W7 (1) 400aa
    Sequence Clusters UniGene:85767 (1)
    Sequence Information (all 16)
    ORTHOLOGY for pdha1b (Chr: 24)
    CITATIONS (20)