Gene
mpc1
- ID
- ZDB-GENE-040718-94
- Name
- mitochondrial pyruvate carrier 1
- Symbol
- mpc1 Nomenclature History
- Previous Names
-
- zgc:92707
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have pyruvate transmembrane transporter activity. Involved in digestive tract development. Predicted to localize to integral component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial pyruvate carrier deficiency. Is expressed in several structures, including digestive system; female organism; head; pectoral fin; and vasculature. Orthologous to human MPC1 (mitochondrial pyruvate carrier 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92707 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Sandoval et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial pyruvate carrier deficiency | Alliance | Mitochondrial pyruvate carrier deficiency | 614741 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR005336 | Mitochondrial pyruvate carrier |
Domain Details Per Protein
| Protein | Length | Mitochondrial pyruvate carrier |
|---|---|---|
|
UniProtKB:F1Q6Z3
|
109 |
Interactions and Pathways
No data available
Plasmids
No data available