ZFIN ID: ZDB-GENE-040718-80
Gene Name: troponin I type 2a (skeletal, fast), tandem duplicate 3
Gene Symbol: tnni2a.3    Nomenclature History

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Previous Names: tropI-1c (1), zgc:92053

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to be involved in cardiac muscle contraction and skeletal muscle contraction. Predicted to localize to troponin complex. Is expressed in muscle; musculature system; myotome; and pectoral fin musculature. Human ortholog(s) of this gene implicated in distal arthrogryposis type 2B1 and intrinsic cardiomyopathy (multiple). Orthologous to several human genes including TNNI2 (troponin I2, fast skeletal type).
Genome Resources: Alliance (1),  Gene:402809 (1),  Ensembl(GRCz11):ENSDARG00000013752 (1)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (8 images) from Thisse et al., 2004 [MGC:92053]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tnni2a.3 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
distal arthrogryposis Alliance Arthrogryposis, distal, type 2B1 601680
distal arthrogryposis type 2B1 Alliance Arthrogryposis, distal, type 2B1 601680
DISEASE ASSOCIATED WITH tnni2a.3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cardiac muscle contraction (more)
Cellular Component troponin complex (more)
Molecular Function molecular_function (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA tnni2a.3-201 (1)    Ensembl 1522
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM tnni2a.3 No data available
MARKER RELATIONSHIPS
tnni2a.3 Contained in: [BAC] DKEY-9F16 (1) (order this)
tnni2a.3 Encodes: [cDNA] MGC:92053 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_205575 (1) 988 nt
Genomic GenBank:CU302206 (1) 64984 nt
Select Tool
Polypeptide UniProtKB:Q6DHU6 (1) 176 aa
Sequence Information (all 13)
ORTHOLOGY for tnni2a.3 ( Chr: 25 )
CITATIONS (21)