ZFIN ID: ZDB-GENE-040718-74
Gene Name: aldehyde dehydrogenase 3 family, member A2a
Gene Symbol: aldh3a2a    Nomenclature History

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Previous Names: aldh3a2 (1), sls (1), wu:fc06b11, zgc:92064

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have 3-chloroallyl aldehyde dehydrogenase activity. Predicted to be involved in cellular aldehyde metabolic process and oxidation-reduction process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Sjogren-Larsson syndrome and arteriosclerosis. Orthologous to human ALDH3A1 (aldehyde dehydrogenase 3 family member A1) and ALDH3A2 (aldehyde dehydrogenase 3 family member A2).
Genome Resources: Alliance (1),  Gene:323653 (1),  Ensembl(GRCz11):ENSDARG00000028259 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92064]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa5879 Point Mutation Unknown Premature Stop ENU
sa18111 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35869 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-aldh3a2a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH aldh3a2a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Sjogren-Larsson syndrome Alliance Sjogren-Larsson syndrome 270200
    DISEASE ASSOCIATED WITH aldh3a2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular aldehyde metabolic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function oxidoreductase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA aldh3a2a-201 (1)    Ensembl 2072
    aldh3a2a-202 (1)    Ensembl 462
    aldh3a2a-204 (1)    Ensembl 664
    ncRNA aldh3a2a-004 (1)    Ensembl 797
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aldh3a2a No data available
    MARKER RELATIONSHIPS
    aldh3a2a Contained in: [BAC] CH211-87M19 (1), CH211-212C13 (1)
    aldh3a2a Encodes: [EST] fc06b11 (1)
    [cDNA] MGC:92064 (1), MGC:173887 (1), MGC:174377 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212649 (1) 1980 nt
    Genomic GenBank:BX548078 (1) 205318 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8PW97 (1) 504 aa
    Sequence Information (all 30)
    ORTHOLOGY for aldh3a2a ( Chr: 15 )
    CITATIONS (29)