Gene

aldh3a2a

ID
ZDB-GENE-040718-74
Name
aldehyde dehydrogenase 3 family, member A2a
Symbol
aldh3a2a Nomenclature History
Previous Names
  • aldh3a2 (1)
  • sls (1)
  • wu:fc06b11
  • zgc:92064
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have 3-chloroallyl aldehyde dehydrogenase activity. Predicted to be involved in cellular aldehyde metabolic process and oxidation-reduction process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Sjogren-Larsson syndrome and arteriosclerosis. Orthologous to human ALDH3A1 (aldehyde dehydrogenase 3 family member A1) and ALDH3A2 (aldehyde dehydrogenase 3 family member A2).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aldh3a2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Sjogren-Larsson syndrome Alliance Sjogren-Larsson syndrome 270200
Associated With aldh3a2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR016160 Aldehyde dehydrogenase, cysteine active site
Conserved_site IPR029510 Aldehyde dehydrogenase, glutamic acid active site
Domain IPR015590 Aldehyde dehydrogenase domain
Family IPR012394 Aldehyde dehydrogenase NAD(P)-dependent
Homologous_superfamily IPR016161 Aldehyde/histidinol dehydrogenase
Homologous_superfamily IPR016162 Aldehyde dehydrogenase, N-terminal
Homologous_superfamily IPR016163 Aldehyde dehydrogenase, C-terminal
Domain Details Per Protein
Protein Length Aldehyde dehydrogenase, C-terminal Aldehyde dehydrogenase, cysteine active site Aldehyde dehydrogenase domain Aldehyde dehydrogenase, glutamic acid active site Aldehyde dehydrogenase NAD(P)-dependent Aldehyde dehydrogenase, N-terminal Aldehyde/histidinol dehydrogenase
UniProtKB:Q6DHU0 488
UniProtKB:A7YYF4 488
UniProtKB:Q90ZZ8 488
UniProtKB:E9QFF0 194
UniProtKB:A0A2R8PW97 504
UniProtKB:E9QE27 116
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations