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ZIRC
ZFIN ID: ZDB-GENE-040718-55
Gene Name: CD36 molecule (thrombospondin receptor)
Gene Symbol: cd36    Nomenclature History

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Previous Name: zgc:92513 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Involved in several processes, including defense response to bacterium; response to prostaglandin; and response to vitamin B3. Localizes to the plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including hemolytic-uremic syndrome; osteoarthritis; pemphigus; platelet-type bleeding disorder 10; and type 2 diabetes mellitus. Is expressed in several structures, including blastoderm; blastodisc; digestive system; pleuroperitoneal region; and taste bud. Orthologous to human CD36 (CD36 molecule).
Genome Resources: Alliance (1),  Gene:436636 (1),  Ensembl(GRCz11):ENSDARG00000032639 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb260 Indel Unknown Unknown CRISPR
ihb261 Small Deletion Exon 3 Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ouc1001 Small Deletion Exon 2 Frameshift, Premature Stop TALEN
    sa9388 Point Mutation Intron 10 Splice Site, Cryptic Donor Splice Site, Exon Loss, Frameshift ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40295 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-cd36 1
    MO1-cd36 N/A 2
    MO2-cd36 N/A 1
    TALEN1-cd36 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cd36 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    platelet-type bleeding disorder 10 Alliance Platelet glycoprotein IV deficiency 608404
    [Macrothrombocytopenia]
    {Coronary heart disease, susceptibility to, 7} 610938
    {Malaria, cerebral, reduced risk of} 611162
    {Malaria, cerebral, susceptibility to} 611162
    DISEASE ASSOCIATED WITH cd36 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process defense response to bacterium (more)
    Cellular Component plasma membrane (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002159 (1)
  • InterPro:IPR005428 (1)
  • InterPro:IPR033076 (1)
  • Pfam:PF01130 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cd36-201 (1)    Ensembl 1880
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cd36 No data available
    MARKER RELATIONSHIPS
    cd36 Contained in: [BAC] DKEY-27K7 (1) (order this)
    cd36 Encodes: [cDNA] MGC:92513 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002363 (1) 1737 bp
    Genomic GenBank:BX897665 (1) 129995 bp
    Select Tool
    Polypeptide UniProtKB:Q6DHC7 (1) 465 aa
    Sequence Clusters UniGene:87300 (1)
    Sequence Information (all 9)
    ORTHOLOGY for cd36 ( Chr: 4 )
    CITATIONS (43)