ZFIN ID: ZDB-GENE-040718-486
Gene Name: ring finger protein 144ab
Gene Symbol: rnf144ab    Nomenclature History

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Previous Names: rnf144 (1), rnf144a, si:dkeyp-7f8.1-001, wu:fj49a04, zgc:92582 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to localize to the cytoplasm and ubiquitin ligase complex. Orthologous to human RNF144A (ring finger protein 144A).
Genome Resources: Alliance (1),  Gene:437000 (1),  Ensembl(GRCz11):ENSDARG00000042557 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92582]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37062 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rnf144ab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rnf144ab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein ubiquitination (more)
    Cellular Component integral component of membrane (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001841 Zinc finger, RING-type
    Domain IPR002867 IBR domain
    Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
    Conserved_site IPR017907 Zinc finger, RING-type, conserved site
    Family IPR031127 E3 ubiquitin ligase RBR family
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rnf144ab-201 (1)    Ensembl 2416
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rnf144ab No data available
    MARKER RELATIONSHIPS
    rnf144ab Contained in: [BAC] DKEYP-7F8 (1)
    rnf144ab Encodes: [EST] fj49a04 (1)
    [cDNA] MGC:92582 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002727 (1) 2287 bp
    Genomic GenBank:BX293564 (1) 145495 bp
    Select Tool
    Polypeptide UniProtKB:Z4YIB5 (1) 294 aa
    Sequence Information (all 16)
    ORTHOLOGY for rnf144ab ( Chr: 20 )
    CITATIONS (24)