Gene

thop1

ID
ZDB-GENE-040718-47
Name
thimet oligopeptidase 1
Symbol
thop1 Nomenclature History
Previous Names
  • fb74b01
  • wu:fb74b01
  • zgc:92139 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have metalloendopeptidase activity. Predicted to be involved in peptide metabolic process and proteolysis. Predicted to localize to mitochondrial intermembrane space. Is expressed in lens. Orthologous to human THOP1 (thimet oligopeptidase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With thop1 Human Ortholog
No data available
Associated With thop1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001567 Peptidase M3A/M3B catalytic domain
Homologous_superfamily IPR024077 Neurolysin/Thimet oligopeptidase, domain 2
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal
Domain Details Per Protein
Protein Length Metallopeptidase, catalytic domain superfamily Neurolysin/Thimet oligopeptidase, domain 2 Neurolysin/Thimet oligopeptidase, N-terminal Peptidase M3A/M3B catalytic domain
UniProtKB:Q6DHR6 686
UniProtKB:X1WF90 176
UniProtKB:E7EZ90 707
UniProtKB:X1WHL0 302
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations