ZFIN ID: ZDB-GENE-040718-440
Gene Name: GATA binding protein 2b
Gene Symbol: gata2b
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:91840 (1)

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding activity transcription factor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity; involved in definitive  ...
GENE EXPRESSION
All Expression Data: 19 figures from 9 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [MGC:91840]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14633 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 5 from Butko et al., 2015
    Observed in:
    DISEASE ASSOCIATED WITH gata2b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute myeloid leukemia {Leukemia, acute myeloid, susceptibility to} 601626
    myelodysplastic syndrome {Myelodysplastic syndrome, susceptibility to} 614286
    Immunodeficiency 21 614172
    Emberger syndrome 614038
    DISEASE ASSOCIATED WITH gata2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process definitive hemopoiesis (more)
    Cellular Component nucleus (more)
    Molecular Function DNA-binding transcription factor activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000679 (1)
  • InterPro:IPR013088 (1)
  • InterPro:IPR016374 (1)
  • InterPro:IPR029522 (1)
  • InterPro:IPR039355 (1)
  • PROSITE:PS00344 (1)
  • PROSITE:PS50114 (1)
  • Pfam:PF00320 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gata2b-201 (1) 1955
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gata2b
    MARKER RELATIONSHIPS
    gata2bContained in: [BAC] CH211-157B11 (1) (order this)
    gata2bEncodes: [cDNA] MGC:91840 (1) (order this), MGC:192890 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002689 (1) 1935bp
    Genomic GenBank:CR450814 (1) 158142bp
    Select Tool
    Polypeptide UniProtKB:F1QD30 (1) 428aa
    Sequence Clusters UniGene:81808 (1)
    Sequence Information (all 16)
    OTHER gata2b GENE PAGES
  • Alliance (1)
  • Gene:436962 (1)
  • VEGA:OTTDARG00000022026 (1)
  • Ensembl(GRCz11):ENSDARG00000009094 (1)
  • ORTHOLOGY for gata2b (Chr: 6)
    CITATIONS (30)