Gene

dnase1

ID
ZDB-GENE-040718-423
Name
deoxyribonuclease I
Symbol
dnase1 Nomenclature History
Previous Names
  • zgc:92440 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and deoxyribonuclease I activity. Predicted to be involved in DNA catabolic process, endonucleolytic. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Orthologous to several human genes including DNASE1 (deoxyribonuclease 1).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dnase1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
systemic lupus erythematosus Alliance {Systemic lupus erythematosus, susceptibility to} 152700
Associated With dnase1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018057 Deoxyribonuclease I, active site
Domain IPR005135 Endonuclease/exonuclease/phosphatase
Family IPR016202 Deoxyribonuclease I
Homologous_superfamily IPR036691 Endonuclease/exonuclease/phosphatase superfamily
Domain Details Per Protein
Protein Length Deoxyribonuclease I Deoxyribonuclease I, active site Endonuclease/exonuclease/phosphatase Endonuclease/exonuclease/phosphatase superfamily
UniProtKB:Q6DG72 278
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations