Gene

pdlim5a

ID

ZDB-GENE-040718-401

Name

PDZ and LIM domain 5a

Symbol

pdlim5a Nomenclature History

Previous Names

pdlim5
ENH (1)
zgc:91978

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable actin binding activity and muscle alpha-actinin binding activity. Predicted to be involved in actin cytoskeleton organization; heart development; and muscle structure development. Predicted to be located in cytoplasm. Predicted to be part of filamentous actin. Predicted to be active in Z disc; adherens junction; and stress fiber. Is expressed in several structures, including cephalic musculature; digestive system; dorsal aorta; nervous system; and notochord. Orthologous to human PDLIM5 (PDZ and LIM domain 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from Ott et al., 2007

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pdlim5a Human Ortholog

No data available

Associated With pdlim5a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001478	PDZ domain
Domain	IPR001781	Zinc finger, LIM-type
Domain	IPR031847	PDZ and LIM domain protein 1-4/Zasp-like, middle domain
Family	IPR050604	PDZ and LIM domain-containing
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M6Z6A6	InterPro	557
UniProtKB:Q6DG04	InterPro	551
UniProtKB:A0A8M9PXB6	InterPro	440
UniProtKB:A0A8M9QDR0	InterPro	332
UniProtKB:A0A8M9Q8D9	InterPro	445
UniProtKB:A0A8M9Q337	InterPro	439
UniProtKB:A0A0R4IN44	InterPro	551
UniProtKB:A0A8M9QDQ6	InterPro	446

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pdlim5a-201 (1) Ensembl	Ensembl	3,781 nt	Select Tool ZFIN BLAST
mRNA	pdlim5a-202 (1) Ensembl	Ensembl	1,659 nt	Select Tool ZFIN BLAST
mRNA	pdlim5a-203 (1) Ensembl	Ensembl	2,944 nt	Select Tool ZFIN BLAST
mRNA	pdlim5a-204 (1) Ensembl	Ensembl	546 nt	Select Tool ZFIN BLAST
mRNA	pdlim5a-205 (1) Ensembl	Ensembl	4,208 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations