ZFIN ID: ZDB-GENE-040718-399
Gene Name: calcium channel, voltage-dependent, beta 1 subunit
Gene Symbol: cacnb1    Nomenclature History

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Previous Names: dihydropyridine receptor b1 (1), red, relaxed, zgc:91982

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Contributes to voltage-gated calcium channel activity. Involved in muscle contraction and voltage-gated calcium channel complex assembly. Localizes to voltage-gated calcium channel complex. Is expressed in several structures, including basal plate midbrain region; hatching gland; musculature system; nervous system; and polster. Orthologous to human CACNB1 (calcium voltage-gated channel auxiliary subunit beta 1).
Genome Resources: Alliance (1),  Gene:436925 (1),  Ensembl(GRCz11):ENSDARG00000002167 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ir1092 Unknown Unknown Unknown
la015086Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • mi90 Point Mutation Unknown Unknown
    sa8705 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33120 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ts25 Point Mutation Exon 13 Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • DISEASE ASSOCIATED WITH cacnb1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cacnb1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process muscle contraction (more)
    Cellular Component voltage-gated calcium channel complex (more)
    Molecular Function protein binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cacnb1-202 (1)    Ensembl 2043
    cacnb1-203 (1)    Ensembl 1670
    cacnb1-205 (1)    Ensembl 1554
    ncRNA cacnb1-004 (1)    Ensembl 690
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cacnb1 No data available
    MARKER RELATIONSHIPS
    cacnb1 Contained in: [BAC] CH211-10J9 (1), DKEY-81L17 (1) (order this)
    cacnb1 Encodes: [cDNA] MGC:91982 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002652 (1) 1680 nt
    Genomic GenBank:CR388097 (1) 195927 nt
    Select Tool
    Polypeptide UniProtKB:Q2Q551 (1) 603 aa
    Sequence Information (all 30)
    ORTHOLOGY for cacnb1 ( Chr: 3 )
    CITATIONS (48)