ZFIN ID: ZDB-GENE-040718-388
Gene Name: acyl-CoA synthetase short chain family member 2
Gene Symbol: acss2    Nomenclature History

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Previous Names: fa04c03, fj80b06, fj80h04, wu:fa04c03, wu:fj80b06, wu:fj80h04, zgc:92200

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have AMP binding activity; ATP binding activity; and acetate-CoA ligase activity. Predicted to be involved in acetyl-CoA biosynthetic process from acetate. Human ortholog(s) of this gene implicated in orofacial cleft. Orthologous to human ACSS2 (acyl-CoA synthetase short chain family member 2).
Genome Resources: Alliance (1),  Gene:436914 (1),  Ensembl(GRCz11):ENSDARG00000037781 (1)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24258 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37622 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-acss2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acss2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH acss2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process acetyl-CoA biosynthetic process from acetate (more)
    Molecular Function acetate-CoA ligase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000873 AMP-dependent synthetase/ligase
    Family IPR011904 Acetate-CoA ligase
    Conserved_site IPR020845 AMP-binding, conserved site
    Domain IPR025110 AMP-binding enzyme, C-terminal domain
    Domain IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain
    Homologous_superfamily IPR042099 AMP-dependent synthetase-like superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acss2-201 (1)    Ensembl 2679
    acss2-203 (1)    Ensembl 837
    acss2-204 (1)    Ensembl 1898
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acss2 No data available
    MARKER RELATIONSHIPS
    acss2 Contained in: [BAC] CH73-268E11 (1), DKEY-66G10 (1) (order this)
    acss2 Encodes: [EST] fa04c03, fj80b06, fj80h04
    [cDNA] MGC:92200 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002641 (1) 2705 bp
    Genomic GenBank:CT027560 (1) 81113 bp
    Select Tool
    Polypeptide UniProtKB:F1QAA7 (1) 698 aa
    Sequence Information (all 27)
    ORTHOLOGY for acss2 ( Chr: 23 )
    CITATIONS (22)