Gene

acss2

ID
ZDB-GENE-040718-388
Name
acyl-CoA synthetase short chain family member 2
Symbol
acss2 Nomenclature History
Previous Names
  • fa04c03
  • fj80b06
  • fj80h04
  • wu:fa04c03
  • wu:fj80b06
  • wu:fj80h04
  • zgc:92200
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have AMP binding activity; ATP binding activity; and acetate-CoA ligase activity. Predicted to be involved in acetyl-CoA biosynthetic process from acetate. Human ortholog(s) of this gene implicated in orofacial cleft. Orthologous to human ACSS2 (acyl-CoA synthetase short chain family member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Tilghman et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With acss2 Human Ortholog
No data available
Associated With acss2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020845 AMP-binding, conserved site
Domain IPR000873 AMP-dependent synthetase/ligase domain
Domain IPR025110 AMP-binding enzyme, C-terminal domain
Domain IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain
Family IPR011904 Acetate-CoA ligase
Homologous_superfamily IPR042099 ANL, N-terminal domain
Homologous_superfamily IPR045851 AMP-binding enzyme, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Acetate-CoA ligase Acetyl-coenzyme A synthetase, N-terminal domain AMP-binding, conserved site AMP-binding enzyme, C-terminal domain AMP-binding enzyme, C-terminal domain superfamily AMP-dependent synthetase/ligase domain ANL, N-terminal domain
UniProtKB:A0A2R8Q6G5 682
UniProtKB:F1QAA7 698
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations