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ZIRC
ZFIN ID: ZDB-GENE-040718-367
Gene Name: interferon regulatory factor 8
Gene Symbol: irf8
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:92252

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in microglia development; regulation of macrophage differentiation; and regulation of neutrophil  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
cq47 Small Deletion Unknown Missense TALEN
cq48 Small Deletion Unknown Premature Stop TALEN
ka90 Unknown Unknown Unknown CRISPR
la013258Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • st95 Small Deletion Unknown Frameshift TALEN
  • European Zebrafish Resource Center (EZRC) (order this)
  • st96 Small Deletion Unknown Frameshift TALEN
    Targeting reagents:
    DISEASE ASSOCIATED WITH irf8 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Immunodeficiency 32B, monocyte and dendritic cell deficiency, autosomal recessive 226990
    Immunodeficiency 32A, mycobacteriosis, autosomal dominant 614893
    DISEASE ASSOCIATED WITH irf8 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hemopoiesis (more)
    Cellular Component nucleus (more)
    Molecular Function DNA-binding transcription factor activity (more)
    GO Terms (all 13)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA irf8-201 (1) 1767
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM irf8
    MARKER RELATIONSHIPS
    irf8Contained in: [BAC] DKEYP-77B5 (1)
    irf8Encodes: [cDNA] MGC:92252 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002622 (1) 1738bp
    Genomic GenBank:BX890541 (1) 94449bp
    Select Tool
    Polypeptide UniProtKB:Q6DHK7 (1) 423aa
    Sequence Clusters UniGene:81006 (1)
    Sequence Information (all 10)
    ORTHOLOGY for irf8 (Chr: 18)
    CITATIONS (84)