ZFIN ID: ZDB-GENE-040718-365
Gene Name: glutathione S-transferase omega 1
Gene Symbol: gsto1    Nomenclature History

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Previous Names: fd58h04, wu:fd58h04, zgc:92254

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have glutathione dehydrogenase (ascorbate) activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to cytoplasm. Is expressed in brain; gill; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Alzheimer's disease and Parkinson's disease. Orthologous to human GSTO1 (glutathione S-transferase omega 1).
Genome Resources: Alliance (1),  Gene:436894 (1),  Ensembl(GRCz11):ENSDARG00000022183 (1)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1913 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2705 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gsto1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gsto1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component cytoplasm (more)
    Molecular Function glutathione transferase activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gsto1-201 (1)    Ensembl 1486
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gsto1 No data available
    MARKER RELATIONSHIPS
    gsto1 Contained in: [BAC] DKEY-51A16 (1) (order this)
    gsto1 Encodes: [EST] fd58h04
    [cDNA] MGC:92254 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002621 (1) 1444 nt
    Genomic GenBank:BX530079 (1) 166397 nt
    Select Tool
    Polypeptide UniProtKB:F1QN72 (1) 240 aa
    Sequence Information (all 11)
    ORTHOLOGY for gsto1 ( Chr: 13 )
    CITATIONS (25)